Androgel is a clear and colorless, hydroalcoholic gel that contains 1%
testosterone. The gel provides a 24-hour continuous delivery of testosterone
transdermally through the application point on the skin. It is estimated to
deliver physiological amounts of testosterone and produces circulating
testosterone concentrations that approximate levels of 298-1043 ng/dL.
Androgel comes as 5G, 7.5G, and 10G containing 50 mg, 75 mg, and 100 mg
respectively for each of testosterone per application. The gel is applied to
clean, dry skin located on the upper arms, shoulders, or abdomen. The gel
dries quickly and provides continuous delivery of testosterone during a
24-hour period. The use of a gel may have advantages for someone who has an
aversion to needles, but the gel is highly inefficient because only 10% of
the testosterone for each application is absorbed into the skin. Therefore,
if 100 mg of testosterone is applied only 10 mg is absorbed.
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