I got the tingle :)

[redguru]

Beta Alanine cause a tingle in the cheeks and ears but not the extremities? Curious if it affects anyone else like this.

[JEAH]

Maybe its a urinary tract infection?

[JEAH]

Hello redguru,

When they enter my buttocks it gets really irritating and next to impossible to stay sitting.

-1000000


This is getting strange.

[kook]

Sounds like everyone is a bit different, I find If there is food in my stomach when I take it then no tingles.

usually when I feel it its all on my back.

[Mrs Croft]

hell I find my lips start getting the tingles and itchy just from drinking the stuff :coolugh: depends on how much I have..but I now have cut down to just under half a tsp..so just mild tingles to face..when I first took it..tingle city :ohnoes: from head to toe..it was VERY distracting when your trying to train.

[Scarlett]

With food, beta alanine makes my eyebrows itch. :lol:

[wags8]

Hello redguru,

Interesting question. I've had the "tingles" in just about every part of my body. When they enter my buttocks it gets really irritating and next to impossible to stay sitting.

-1000000

WARNING! Do not let the tingles enter your buttocks. RUN! RUUUUUNNNNN!!!

[MR.cashcream]

WARNING! Do not let the tingles enter your buttocks. RUN! RUUUUUNNNNN!!!

:rofl:


When they enter my buttocks it gets really irritating and next to impossible to stay sitting.


LMAO, this is crazy

[MR.cashcream]

Ohh, as for the topic at hand, RG, I've had the tingles in the back of my neck and run up thru my ears n face as well before. Somedays it's different nit'll be my arms or my legs, just depends on where those tingles decide to pop up, :lol:

[xrsist]

i feel it mainly in my foreamrs, sometimes legs

[redguru]

hell I find my lips start getting the tingles and itchy just from drinking the stuff :coolugh: depends on how much I have..but I now have cut down to just under half a tsp..so just mild tingles to face..when I first took it..tingle city :ohnoes: from head to toe..it was VERY distracting when your trying to train.

I agree, it was very distracting :)

[Ulter]

For me it goes the same way every time.
Tongue
Face
Arms
Fingers

I take it orally so I don't get the butt thing goin on

[Bmoore535]

I have the same problem, I feel like im not real, The tingling irritates me but n a weird way makes me feel more than a man, like theres lighting flowing through my body

[KOArtist]

Is it something that you eventually get acclimated to, or is it tingles forever?

[macrophage69 alpha]

Is it something that you eventually get acclimated to, or is it tingles forever?

there is usually some acclimation, but at moderate to high dosing there is usually at least some tingle (though typically any unpleasantness to the tingle dissipates- for those that find it so in the beginning)

[Sarge]

I feel it on my arms, fingers.

DO NOT shower after taking it... feels weird as hell!

[KOArtist]

Just took my first teaspoon...headed to the gym in a few. I'll post my experiences when I get back if I'm not a tingling itchy mess, haha.

[KOArtist]

Pretty crazy stuff...I played 3 full games of pickup hoops after I lifted, and I was still ready to keep playing which is pretty unusual, so I guess I definitely felt the endurance effects, unless I just coincidentally had a "good day". Do you guys have endurance athletes on the stuff?

[badgergrl]

What exactly causes the "tingles"??

[macrophage69 alpha]

Pretty crazy stuff...I played 3 full games of pickup hoops after I lifted, and I was still ready to keep playing which is pretty unusual, so I guess I definitely felt the endurance effects, unless I just coincidentally had a "good day". Do you guys have endurance athletes on the stuff?

http://www.afboard.com/forum/anafit-supplement-discussion/962-how-close-my-workouts-should-i-take.html

[macrophage69 alpha]

Hello, I've been looking for a peer reviewed study supporting Beta Alanine, can you please post some if you have any? Thank you.


there are peer reviewed studies, that being said and in all fairness cannot judge the quality of that review (though the same can be said for many journals and studies for that matter). The studies and anecdotals are certainly positive.

: J Strength Cond Res. 2006 Nov;20(4):928-31.Links
Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold.Stout JR, Cramer JT, Mielke M, O'Kroy J, Torok DJ, Zoeller RF.
Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA. jrstout@ou.edu

The purpose of this study was to examine the effects of 28 days of beta-alanine (b-Ala) and creatine monohydrate (CrM) supplementation on the onset of neuromuscular fatigue by using the physical working capacity at neuromuscular fatigue threshold (PWC(FT)) test in untrained men. Fifty-one men (mean age +/- SD = 24.5 +/- 5.3 years) volunteered to participate in this 28-day, double-blind, placebo-controlled study and were randomly assigned to 1 of 4 groups: placebo (PLA; 34 g dextrose; n = 13), CrM (5.25 g CrM plus 34 g dextrose; n = 12), b-Ala (1.6 g b-Ala plus 34 g of dextrose; n = 12), or b-Ala plus CrM (CrBA; 5.25 g CrM plus 1.6 g b-Ala plus 34 g dextrose; n = 14). The supplement was ingested 4 times per day for 6 consecutive days, then twice per day for 22 days before posttesting. Before and after the supplementation, subjects performed a continuous incremental cycle ergometry test while a surface electromyographic signal was recorded from the vastus lateralis muscle to determine PWC(FT). The adjusted mean posttest PWC(FT) values (covaried for pretest PWC(FT) values) for the b-Ala and CrBA groups were greater than those for the PLA group (p < or = 0.05). However, there were no differences between the CrM vs. PLA, CrBA vs. b-Ala, CrM vs. b-Ala, or CrM vs. CrBA groups (p > 0.05). These findings suggested that b-Ala supplementation may delay the onset of neuromuscular fatigue. Furthermore, there appeared to be no additive or unique effects of CrM vs. b-Ala alone on PWC(FT).

J Appl Physiol. 2007 Nov;103(5):1736-43. Epub 2007 Aug 9. Links
beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.Derave W, Ozdemir MS, Harris RC, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E.
Dept. of Movement and Sport Sciences, Ghent Univ., Watersportlaan 2, B-9000 Ghent, Belgium. Wim.derave@ugent.be

Carnosine (beta-alanyl-l-histidine) is present in high concentrations in human skeletal muscle. The ingestion of beta-alanine, the rate-limiting precursor of carnosine, has been shown to elevate the muscle carnosine content. We aimed to investigate, using proton magnetic resonance spectroscopy (proton MRS), whether oral supplementation with beta-alanine during 4 wk would elevate the calf muscle carnosine content and affect exercise performance in 400-m sprint-trained competitive athletes. Fifteen male athletes participated in a placebo-controlled, double-blind study and were supplemented orally for 4 wk with either 4.8 g/day beta-alanine or placebo. Muscle carnosine concentration was quantified in soleus and gastrocnemius by proton MRS. Performance was evaluated by isokinetic testing during five bouts of 30 maximal voluntary knee extensions, by endurance during isometric contraction at 45% maximal voluntary contraction, and by the indoor 400-m running time. beta-Alanine supplementation significantly increased the carnosine content in both the soleus (+47%) and gastrocnemius (+37%). In placebo, carnosine remained stable in soleus, while a small and significant increase of +16% occurred in gastrocnemius. Dynamic knee extension torque during the fourth and fifth bout was significantly improved with beta-alanine but not with placebo. Isometric endurance and 400-m race time were not affected by treatment. In conclusion, 1) proton MRS can be used to noninvasively quantify human muscle carnosine content; 2) muscle carnosine is increased by oral beta-alanine supplementation in sprint-trained athletes; 3) carnosine loading slightly but significantly attenuated fatigue in repeated bouts of exhaustive dynamic contractions; and 4) the increase in muscle carnosine did not improve isometric endurance or 400-m race time.

PMID: 17690198 [PubMed - indexed for MEDLINE]
1: Amino Acids. 2007 Feb;32(2):225-33. Epub 2006 Jul 28. Links
Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA.
School of Sports, Exercise & Health Sciences, University of Chichester, Chichester, UK.

Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyn) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (Wmax). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. Muscle carnosine was significantly increased by +58.8% and +80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 4 wks beta-alanine supplementation resulted in a significant increase in TWD (+13.0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine.


Amino Acids. 2007;32(3):381-6. Epub 2006 Nov 30. Links
Effects of beta-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women.Stout JR, Cramer JT, Zoeller RF, Torok D, Costa P, Hoffman JR, Harris RC, O'Kroy J.
Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019-6081, USA. jrstout@ou.edu

This study examined the effects of 28 days of beta-alanine supplementation on the physical working capacity at fatigue threshold (PWCFT), ventilatory threshold (VT), maximal oxygen consumption (VO2-MAX), and time-to-exhaustion (TTE) in women. Twenty-two women (age+/-SD 27.4+/-6.1 yrs) participated and were randomly assigned to either the beta-alanine (CarnoSyn) or Placebo (PL) group. Before (pre) and after (post) the supplementation period, participants performed a continuous, incremental cycle ergometry test to exhaustion to determine the PWCFT, VT, VO2-MAX, and TTE. There was a 13.9, 12.6 and 2.5% increase (p<0.05) in VT, PWCFT, and TTE, respectively, for the beta-alanine group, with no changes in the PL (p>0.05). There were no changes for VO2-MAX (p>0.05) in either group. Results of this study indicate that beta-alanine supplementation delays the onset of neuromuscular fatigue (PWCFT) and the ventilatory threshold (VT) at submaximal workloads, and increase in TTE during maximal cycle ergometry performance. However, beta-alanine supplementation did not affect maximal aerobic power (VO2-MAX). In conclusion, beta-alanine supplementation appears to improve submaximal cycle ergometry performance and TTE in young women, perhaps as a result of an increased buffering capacity due to elevated muscle carnosine concentrations.

[macrophage69 alpha]

1: Int J Sports Med. 2008 Jun 11. [Epub ahead of print] Links
beta-Alanine and the Hormonal Response to Exercise.Hoffman J, Ratamess NA, Ross R, Kang J, Magrelli J, Neese K, Faigenbaum AD, Wise JA.
Health and Exercise Science, The College of New Jersey, Ewing, New Jersey, United States.

The effect of 30 days of beta-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with 1.5 minutes of rest between sets was performed before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (**), 15-minutes (15P) and 30-minutes (30P) postexercise for growth hormone, testosterone and cortisol concentrations. A 22 % (p < 0.05) difference in total number of repetitions performed at the end of 4 weeks of supplementation was seen between beta-alanine (BA) and placebo (PL), and Delta mean power was greater in BA (98.4 +/- 43.8 w) vs. PL (7.2 +/- 29.6 w). Growth hormone concentrations were elevated from BL at ** and 15P for both groups, while cortisol concentrations were greater than BL at all time points for both BA and PL. No group differences were noted. No change from BL was seen in testosterone concentrations for either group. Results indicate that four weeks of beta-alanine supplementation can significantly improve muscular endurance during resistance training in experienced resistance-trained athletes. However, these performance gains did not affect the acute endocrine response to the exercise stimulus.

[Gettinripped]

what benefits, if any, would one see or realize from increasing the dosage??

I'm currently using the prescribed 1 tsp pre and post w/o with my shake.

i'm using purcee and redblast as well.

i've been running it for about a month now and the tingles have subsided.

[Ulter]

I don't get the tingles some days and other it's crazy. I think how much food I ate is the reason. Food = less tingle.
I am really energized on 1 heaping tsp. I don't think I would need more than that.

[Blade85]

I don't get the tingles some days and other it's crazy. I think how much food I ate is the reason. Food = less tingle.
I am really energized on 1 heaping tsp. I don't think I would need more than that.

same here.

word of advice to all. say in the winter time, your out riding your bike and get chapped lips. DO NOT, I repeat DO NOT let BA get on your lips. You will want to die.

[Doggy]

Be sure to use a tsp & not a TBS such as I did= major tingle, jingle jangle!

[Blade85]

Be sure to use a tsp & not a TBS such as I did= major tingle, jingle jangle!

Im up to a tablespoon

[macrophage69 alpha]

some people can tolerate the higher doses, but for first timers and novices it can be very unpleasant.

also high doses can affect blood sugar, especially if not used to them (this may be a beneficial effect if dosed appropriately and accounted for (in insulin insensitive or glucose clearance challenged individuals)

[BIG SMT]

I noticed taking it on an empty stomach makes the tingle much worse. Just to let others know.

[macrophage69 alpha]

I noticed taking it on an empty stomach makes the tingle much worse. Just to let others know.

yes, it does. for people that are sensitive to this effect its generally reccomended that it be taken with food or in smaller doses.

some people crave the tingle (so if you want more tingle, empty stomach first and then if needed increase the dose)

[Elle]

Hey I have no clue!

I just saw the words "tingle" and "RedGuru" together so had to come say hi! :wavey:

[cipherkingtoo]

it makes me feel like i have pins and needles in my shirt. i get it bad on my back and my arms.