Time till oxandrolone suppresses HPTA?

[DaMan]

I'm considering using BTG Oxandrins as an anticatabolic for future DNP runs (yes yes I know you all hate DNP that's not the point here) and am wondering how long till ox suppresses the HPTA... I know its effect on protein synthesis/degradation takes place within two or three days which is good, and I usually limit my DNP cycles to a week... but obviously if it's gonna hit my LH or test in less than 10 days that would not be so great...

Studies?

Thanks!

[archive_Ulter]

It inhibits the HPTA by the 5-6th day. But it may never shut you down completely. In some studies that were done to determine if Ox shuts down LH the boys only experienced a drop of 34-89%[1]. But they were still not shut down completely.


[1]J Pediatr 1979 Apr;94(4):657-62

The effect of synthetic androgens on the hypothalamic-pituitary-gonadal axis in boys with constitutionally delayed growth.

Hopwood NJ, Kelch RP, Zipf WB, Hernandez RJ.

[DaMan]

<BLOCKQUOTE class="**-ubbcode-quote"><font size="-1">quote:</font><HR>Originally posted by Ulter:
It inhibits the HPTA by the 5-6th day. But it may never shut you down completely. In some studies that were done to determine if Ox shuts down LH the boys only experienced a drop of 34-89%[1]. But they were still not shut down completely.


[1]J Pediatr 1979 Apr;94(4):657-62

The effect of synthetic androgens on the hypothalamic-pituitary-gonadal axis in boys with constitutionally delayed growth.

Hopwood NJ, Kelch RP, Zipf WB, Hernandez RJ.<HR></BLOCKQUOTE>

Saw that study already, thx - unfortunately those percentages are after 6 months and the abstract doesn't give details re when suppression begins... so I'll trust you on the 4-6 day thing - thanks again!

Reason I'm asking is cuz I really don't want to have to clomid after a measly 7-day DNP/ox run.

BTW any thoughts on dbol for the same purpose?

[archive_Dancer]

http://jcem.endojournals.org/cgi/content/full/84/8/2705


'Total serum T concentrations were within normal physiological range on day 0 (449 ± 35 ng/dL) and day 3 (441 ± 44 ng/dL) of OX treatment. However, by day 5, total serum T concentrations were significantly reduced (282 ± 45 ng/dL; P < 0.05) below day 0 and day 3 values [Fig. 3). Serum free T concentrations were within normal physiological range on days 0, 3, and 5. However, by day 5, serum free T concentrations were significantly reduced [98 ± 10 pg/mL; P < 0.001) below day 0 [121 ± 12 pg/mL) and day 3 [126 ± 9 pg/mL) values. Hence, the total androgen concentration [T + OX) was reduced in parallel to the reduction in T [Fig. 3).'



Half life is 9 hours you might as well use halo.

First I learned to forgive myself, then I told myself do whatever you want it's fine with me. [img]/infopop/emoticons/icon_smile.gif[/img]

[DaMan]

<BLOCKQUOTE class="**-ubbcode-quote"><font size="-1">quote:</font><HR>Originally posted by Dancer:
http://jcem.endojournals.org/cgi/content/full/84/8/2705


'Total serum T concentrations were within normal physiological range on day 0 (449 ± 35 ng/dL) and day 3 (441 ± 44 ng/dL) of OX treatment. However, by day 5, total serum T concentrations were significantly reduced (282 ± 45 ng/dL; P < 0.05) below day 0 and day 3 values [Fig. 3). Serum free T concentrations were within normal physiological range on days 0, 3, and 5. However, by day 5, serum free T concentrations were significantly reduced [98 ± 10 pg/mL; P < 0.001) below day 0 [121 ± 12 pg/mL) and day 3 [126 ± 9 pg/mL) values. Hence, the total androgen concentration [T + OX) was reduced in parallel to the reduction in T [Fig. 3).'



Half life is 9 hours you might as well use halo.

First I learned to forgive myself, then I told myself do whatever you want it's fine with me. [img]/infopop/emoticons/icon_smile.gif[/img]<HR></BLOCKQUOTE>

Shit, that bodes pretty well for dbol.

Who did they test, and at what dosages?

Thx.

[archive_Ulter]

I really think you're over-thinking this. Your HPTA will view this as a blip. Your natural test levels go up and down within a week all throughout your life. My point was that after several months the HPTA was still working. The purpose of clomid is to get the HPTA started again. You don't need to get it started again if it isn't shut down in the first place.

[Fonz]

<BLOCKQUOTE class="**-ubbcode-quote"><font size="-1">quote:</font><HR>Originally posted by Dancer:
http://jcem.endojournals.org/cgi/content/full/84/8/2705


'Total serum T concentrations were within normal physiological range on day 0 (449 ± 35 ng/dL) and day 3 (441 ± 44 ng/dL) of OX treatment. However, by day 5, total serum T concentrations were significantly reduced (282 ± 45 ng/dL; P < 0.05) below day 0 and day 3 values [Fig. 3). Serum free T concentrations were within normal physiological range on days 0, 3, and 5. However, by day 5, serum free T concentrations were significantly reduced [98 ± 10 pg/mL; P < 0.001) below day 0 [121 ± 12 pg/mL) and day 3 [126 ± 9 pg/mL) values. Hence, the total androgen concentration [T + OX) was reduced in parallel to the reduction in T [Fig. 3).'



Half life is 9 hours you might as well use halo.

First I learned to forgive myself, then I told myself do whatever you want it's fine with me. [img]/infopop/emoticons/icon_smile.gif[/img]<HR></BLOCKQUOTE>

If only i could find some damn halo here.

In the UK, you could pick it off the trees, here......nothing.

And I need it to. (Arghh!)

Fonz

No Pain....No Gain.....No Spain

----Barcelona 1992

[archive_Mr. Nobody]

Anticatabolics:
Vitamin C 3000mg before working out
DHEA 150-200mg am and post workout
Insulin after workout and/or am.
dbol 10mg am
PS(phosphasomething...Syrene) 400mg am, 400mg post workout
cytadren (also anti-aromatize at 250mg am and 250mg post workout)....makes you very sleep though,
ephedrine I seem to remember keeps catabolism at bay as well

there is plenty more like Vitamin A, zinc, ginko biloba and such, that help too

No need to do all of the above, pick whats right for you
Dont overdo the cortisol suppression though, your joints will tell you.

Disclaimer:
Mr. Nobody is presenting fictitious opinions and does in no way, shape or form encourage, use nor condone the use of any illegal substances or the use of legal substances in an illegal manner.
The information discussed is strictly for entertainment purposes only and shall not take the place of qualified medical advise.

[Fonz]

<BLOCKQUOTE class="**-ubbcode-quote"><font size="-1">quote:</font><HR>Originally posted by Mr. Nobody:
Anticatabolics:
Vitamin C 3000mg before working out
DHEA 150-200mg am and post workout
Insulin after workout and/or am.
dbol 10mg am
PS(phosphasomething...Syrene) 400mg am, 400mg post workout
cytadren (also anti-aromatize at 250mg am and 250mg post workout)....makes you very sleep though,
ephedrine I seem to remember keeps catabolism at bay as well

there is plenty more like Vitamin A, zinc, ginko biloba and such, that help too

No need to do all of the above, pick whats right for you
Dont overdo the cortisol suppression though, your joints will tell you.

_Disclaimer:
Mr. Nobody is presenting fictitious opinions and does in no way, shape or form encourage, use nor condone the use of any illegal substances or the use of legal substances in an illegal manner.
The information discussed is strictly for entertainment purposes only and shall not take the place of qualified medical advise._
<HR></BLOCKQUOTE>

Cytadren?

Have to disagree with you there Mr. N.

Aminogluthemide is absolute garbage for conrtisol
control.

Too unpredctable and hard to dose.

Fonz

No Pain....No Gain.....No Spain

----Barcelona 1992