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Anafit Supplement Discussion Discuss the effects and uses of Anafit Products such as SesaPure, PureCEE, AIFM and Glucorell-R.

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Old 09-10-2008, 08:42 PM   #1 (permalink)
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Default Sesapure for fatloss?

How helpful is Sesapure with regard to fatloss? I think Macro once mentioned that it works very well to minimize fat gain on a hypercaloric diet but that it is of limited benefit when it comes to fatloss. What is the final word on that?
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Old 09-10-2008, 10:53 PM   #2 (permalink)
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It's great for fatloss. It wastes the calories you don't use so you're able to keep off fat while overeating. But it's equally beneficial when dieting.
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Old 09-10-2008, 11:45 PM   #3 (permalink)
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Does it dispose only of fat based calories or all calories in surplus?
Im not familiar with the product or its mechanisms and im sure thats somewhat of an oversimplification so excuse my ignorance.
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Old 09-11-2008, 12:29 AM   #4 (permalink)
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Surplus fat and sugars. You'll make an extra trip to the bathroom each day, most likely.
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Old 09-11-2008, 12:46 AM   #5 (permalink)
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Cool deal. Olivia has some, i didnt wana go diggin thru her purse tho.
Thanks for the reply mang, sounds cool for someone on a perma-bulk like my fatass.
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Old 09-11-2008, 12:47 AM   #6 (permalink)
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So that's how it helps with surplus calories but what is the benefit when you already have a big calorie deficit?
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Old 09-11-2008, 11:22 AM   #7 (permalink)
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Maybe off the path here a bit but will it help clean ot the intestines at all? Anything close to colon cleanze?

I used it in the past and the bathroom trips were, how would you say.....more productive.


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Old 09-11-2008, 11:25 AM   #8 (permalink)
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That's the increase in your metabolism. Here's the post Macro just put up on the other thread.

Sesamin & R-ALA studies?
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Old 09-11-2008, 04:08 PM   #9 (permalink)
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Quote:
Originally Posted by xtinct View Post
So that's how it helps with surplus calories but what is the benefit when you already have a big calorie deficit?
sesamin/episesamin reduces lipogenic enzymes, which even with a calorie deficit are still present (obviously there is more impact to this when there is calorie excess).

sesamin/episesamin (episesamin in particular) also induces fatty acid utilization and oxidation. This impact will be significant in both hypo and hyper caloric states.

that being said:

sesamin/episesamin is generally more potent and consistent across the population when it comes to impacts on hypercaloric state (overfeeding). ie the effects (fattyness prevention ) are noticeable by pretty much everyone.

The impacts on the hypocaloric state (starvin marvin) are less consistent, particularly when it comes to potency, across the population. ie. the impact on fat loss and metabolic stimulus varies more between persons. This may be offset by higher dosing (though not necessarily).

while its not been specifically looked at, due to its interaction with pparalpa, sesamin/episesamin (again more episesamin) likely increase human uncoupling protein levels as well as other enzymes and proteins associated with high metabolic rate. it has been specifically shown to increase acyl-CoA thioesterase, 3-ketoacyl-CoA thiolase, acyl-CoA oxidase and carnitine palmitoyltranferase.
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Old 09-21-2008, 02:40 PM   #10 (permalink)
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Quote:
Originally Posted by macrophage69alpha View Post
sesamin/episesamin reduces lipogenic enzymes, which even with a calorie deficit are still present (obviously there is more impact to this when there is calorie excess).

sesamin/episesamin (episesamin in particular) also induces fatty acid utilization and oxidation. This impact will be significant in both hypo and hyper caloric states.

that being said:

sesamin/episesamin is generally more potent and consistent across the population when it comes to impacts on hypercaloric state (overfeeding). ie the effects (fattyness prevention ) are noticeable by pretty much everyone.

The impacts on the hypocaloric state (starvin marvin) are less consistent, particularly when it comes to potency, across the population. ie. the impact on fat loss and metabolic stimulus varies more between persons. This may be offset by higher dosing (though not necessarily).

while its not been specifically looked at, due to its interaction with pparalpa, sesamin/episesamin (again more episesamin) likely increase human uncoupling protein levels as well as other enzymes and proteins associated with high metabolic rate. it has been specifically shown to increase acyl-CoA thioesterase, 3-ketoacyl-CoA thiolase, acyl-CoA oxidase and carnitine palmitoyltranferase.
It wouldn't seem that Sesapure would have any CNS stimulating effects like Thermorexin or Cardio Breeze. Can you confirm I'm right about that? I'm particularly sensitive to any kind of stimulants and want to avoid that. Also, it's my impression that the user consensus about Thermorexin is that it's the most potent fatloss supp you offer. Would you say that Sesapure is at least comparable to it in terms of efficacy?

Thanks.
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Old 09-21-2008, 03:54 PM   #11 (permalink)
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Sesapure/Glucorell is as effective for most people as Thermorexin in terms of fat loss. They do not affect the CNS and so many people prefer that combo.
Thermorexin may have the edge because it suppresses your appetite and gives more energy allowing you to train better. But for your situation the S/G combo would be the best choice.
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Old 09-21-2008, 05:21 PM   #12 (permalink)
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it does not have any stimulant effects. when it comes to effectiveness, thats really going to vary. In some people it will have more lipolytic effects and in others it wont. (note- higher end dosing with sesapure MAY alter this- but at general dosing parameters- 4-6 caps per day- it cannot be said that sesapure across the population is comparable or more potent for fat loss than thermorexin (directly it may be, but the increased activity level and ability to sustain activity that thermorexin provides is significant).


ie. two people lay around and dont do much, sesapure may be generally as or more effective than thermorexin.

ie with two active people, where thermorexin allows for "more intense/extended" activity sesapure MAY be as or more effective but generally this cannot be said for all users. note- In women and men with estro fat pattern, sesapure does tend to be more potent a lipolytic

when it comes to overeating, sesapure is certainly generally significantly better for damage control. (even more so than activity offset of thermorexin)
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Old 09-21-2008, 09:13 PM   #13 (permalink)
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Just the info I was looking for. Thanks guys.
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Old 09-21-2008, 09:53 PM   #14 (permalink)
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Note: My response is based soley on our customer's accounts of their results over the past few years and can not be found in medical literature.
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