Nettle root (urtica dioca)

macrophage69alpha · 05-07-2008, 07:06 AM

commonly used in "testosterone boosters", for its ability to either inhibit or bind to SHBG, can cause gynecomastia.

N Z Med J. 2007 Nov 9;120(1265):U2803.Links
Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica).Sahin M, Yilmaz H, Gursoy A, Demirel AN, Tutuncu NB, Guvener ND.
Endocrinology and Metabolic Diseases Department, Baskent University, Ankara, Turkey. drsahinmustafa@yahoo.com

Nettle (Urtica dioica) is commonly sold as a herbal tea in Turkey. We report a case of gynaecomastia in a man (in which the only aetiologic factor identified was nettle tea consumption) and a case of galactorrhoea in a woman (in which the only aetiologic factor identified was also nettle tea ingestion).

PMID: 18264183 [PubMed - indexed for MEDLINE]

while SHBG levels are best at the lower end of the spectrum (and can cause issues at the high end), like many things lowering them too much can cause issues.

arguably these are isolated cases, however in light of the impact of the HIV/Oxandrolone/SHBG suppression study and its impact on hormone levels... its something that bears looking into.

mike · 08-17-2008, 01:45 PM

i actually just picked up some:

"Stinging Nettles 480mg" ... 480mg of Stinging Nettles (Uritica Dioica) (leaf)..

i was concerned my shbg might be outta control due to me being on HRT for so long...

this is the leaf though, and not the root -- i couldnt find the root locally...

thoughts on dose?

macrophage69alpha · 08-17-2008, 02:08 PM

why not get blood work before making such a leap?

there is evidence that the reason that super high doses are needed for some individuals is not because they have high SHBG but rather that they have LOW shbg.

as a note- trenbolone is not bound by SHBG and is a heavy suppressor of SHBG (most orals also heavily suppress SHBG)

mike · 08-17-2008, 02:11 PM

Quote:

Originally Posted by macrophage69alpha

why not get blood work before making such a leap?

there is evidence that the reason that super high doses are needed for some individuals is not because they have high SHBG but rather that they have LOW shbg.

as a note- trenbolone is not bound by SHBG and is a heavy suppressor of SHBG (most orals also heavily suppress SHBG)

i only use test.. isnt it a safe assumptino to believe that my shbg is pretty high? i've been 'on' for years now.. is it that big of a leap to take nettle root?

and is 480mg of the leaf considered a "super high dose?"

i am unable to tell if the 'leaf' is different from the 'root', or if some manufacturers just label it differently. i assume there is probably a difference in the potency, hence the leaf having a higher dosage.

mike · 08-17-2008, 02:43 PM

here's what I got, btw.

like I said.. ic ouldnt find the root extract at the store..

Blut Wump · 08-17-2008, 03:11 PM

My understanding is that the root rather than the leaf holds the actives for suppression of SHBG. The leaves are typically used for tea concoctions and infusions.

mike · 08-17-2008, 03:17 PM

Quote:

Originally Posted by Blut Wump

My understanding is that the root rather than the leaf holds the actives for suppression of SHBG. The leaves are typically used for tea concoctions and infusions.

well shit on me.

mike · 08-17-2008, 03:18 PM

i actually think they had this..i will exchange it.

Nettle Root by Solaray - VitaminShoppe.com

macrophage69alpha · 08-17-2008, 06:47 PM

Quote:

Originally Posted by mike

i only use test.. isnt it a safe assumptino to believe that my shbg is pretty high? i've been 'on' for years now.. is it that big of a leap to take nettle root?

and is 480mg of the leaf considered a "super high dose?"

i am unable to tell if the 'leaf' is different from the 'root', or if some manufacturers just label it differently. i assume there is probably a difference in the potency, hence the leaf having a higher dosage.

no

...hmm...

extraction and lignan contents (prior to extraction) are what will vary... have not looked at differences.. lignans are most concentrated in root. leaf is used for its lectin content, which are in theory immunomodulatory...

Blut Wump · 08-17-2008, 06:52 PM

It's never too late to start a biology course...

Lectins are sugar-binding proteins which are highly specific for their sugar moieties. They typically play a role in biological recognition phenomena involving cells and proteins. For example, some bacteria use lectins to attach themselves to the cells of the host organism during infection.

mike · 08-17-2008, 08:16 PM

i exchanged it for the other one. i'll be taking 1/day. hope it helps with some gains and libido, etc.

Jarconis · 08-18-2008, 12:11 AM

think haaaaaarder/rafiki

05-07-2008, 07:06 AM	#1 (permalink)
macrophage69alpha experiment gone awry Join Date: Feb 2000 Posts: 5,046 Rep Power: 41031	Nettle root (urtica dioca) commonly used in "testosterone boosters", for its ability to either inhibit or bind to SHBG, can cause gynecomastia. N Z Med J. 2007 Nov 9;120(1265):U2803.Links Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica).Sahin M, Yilmaz H, Gursoy A, Demirel AN, Tutuncu NB, Guvener ND. Endocrinology and Metabolic Diseases Department, Baskent University, Ankara, Turkey. drsahinmustafa@yahoo.com Nettle (Urtica dioica) is commonly sold as a herbal tea in Turkey. We report a case of gynaecomastia in a man (in which the only aetiologic factor identified was nettle tea consumption) and a case of galactorrhoea in a woman (in which the only aetiologic factor identified was also nettle tea ingestion). PMID: 18264183 [PubMed - indexed for MEDLINE] while SHBG levels are best at the lower end of the spectrum (and can cause issues at the high end), like many things lowering them too much can cause issues. arguably these are isolated cases, however in light of the impact of the HIV/Oxandrolone/SHBG suppression study and its impact on hormone levels... its something that bears looking into.

Thread Tools
Show Printable Version Email this Page
Display Modes
Linear Mode Switch to Hybrid Mode Switch to Threaded Mode

Helpful links suggested by members
Cycles for Pennies a day by DC	The original thread by Dogg Crapp aka Dante
Pubmed	National Institute of Health Public Library.
Real Sports Report on Steroids	The truth about steroids that only HBO would present. MP4 Large file. Use Real Player
Merck Medical Manual	Merck manual of medical information
AAS: Mechanism of Action and Effects on Performance	Encyclopedia of Sports Medicine and Science California State Univ. Explanation of AAS effects on athletes
Carlorie King	The world's largest food database
ExRx Exercise and Muscle Directory	Exercises by muscle parts and vice versa. Includes video of popular exercises.
Wholesale Hair Products	Nizoral and other hair products
USDA National Nutrient Database	The nutritional value of all foods.
Fitday.com	Detailed Nutrition for 1,000's of foods with macro breakdowns
List of brand names for drugs	What various drugs are called by name brands around the world.
Getpinz.com	Medical and lab supplies
Health Tests Direct	Blood tests by mail without a prescription

08-17-2008, 01:45 PM	#2 (permalink)
mike Powered by Anafit Join Date: Feb 2006 Location: Orlando, FL Posts: 2,326 Rep Power: 22388	i actually just picked up some: "Stinging Nettles 480mg" ... 480mg of Stinging Nettles (Uritica Dioica) (leaf).. i was concerned my shbg might be outta control due to me being on HRT for so long... this is the leaf though, and not the root -- i couldnt find the root locally... thoughts on dose?

08-17-2008, 02:08 PM	#3 (permalink)
macrophage69alpha experiment gone awry Join Date: Feb 2000 Posts: 5,046 Rep Power: 41031	why not get blood work before making such a leap? there is evidence that the reason that super high doses are needed for some individuals is not because they have high SHBG but rather that they have LOW shbg. as a note- trenbolone is not bound by SHBG and is a heavy suppressor of SHBG (most orals also heavily suppress SHBG)

08-17-2008, 02:43 PM	#5 (permalink)
mike Powered by Anafit Join Date: Feb 2006 Location: Orlando, FL Posts: 2,326 Rep Power: 22388	here's what I got, btw. like I said.. ic ouldnt find the root extract at the store..

08-17-2008, 03:11 PM	#6 (permalink)
Blut Wump The Venerable Wump Join Date: Feb 2007 Location: UK Posts: 7,241 Rep Power: 323832	My understanding is that the root rather than the leaf holds the actives for suppression of SHBG. The leaves are typically used for tea concoctions and infusions.

08-17-2008, 03:18 PM	#8 (permalink)
mike Powered by Anafit Join Date: Feb 2006 Location: Orlando, FL Posts: 2,326 Rep Power: 22388	i actually think they had this..i will exchange it. Nettle Root by Solaray - VitaminShoppe.com

08-17-2008, 06:52 PM	#10 (permalink)
Blut Wump The Venerable Wump Join Date: Feb 2007 Location: UK Posts: 7,241 Rep Power: 323832	It's never too late to start a biology course... Lectins are sugar-binding proteins which are highly specific for their sugar moieties. They typically play a role in biological recognition phenomena involving cells and proteins. For example, some bacteria use lectins to attach themselves to the cells of the host organism during infection.

08-17-2008, 08:16 PM	#11 (permalink)
mike Powered by Anafit Join Date: Feb 2006 Location: Orlando, FL Posts: 2,326 Rep Power: 22388	i exchanged it for the other one. i'll be taking 1/day. hope it helps with some gains and libido, etc.

08-18-2008, 12:11 AM	#12 (permalink)
Jarconis AF Member Join Date: Aug 2008 Posts: 78 Rep Power: 3448	think haaaaaarder/rafiki